Bài viết
26/12/2023
Colorectal cancer, a formidable global health challenge, ranks among the top three cancers worldwide and remains a significant contributor to cancer-related mortality. Early diagnosis through colonoscopy, aimed at detecting and removing adenomatous polyps, is pivotal in mitigating colorectal cancer risk. Studies indicate that a mere 1% increase in adenoma detection rate corresponds to a noteworthy 3% decrease in cancer risk. However, the persisting challenge lies in the estimated 27% rate of missed adenomas during endoscopic procedures, often attributed to cognitive or technical errors. In recent times, the integration of artificial intelligence (AI) into colonoscopies has been explored as a potential solution to enhance polyp detection, thereby minimizing human error. Despite these advancements, concerns regarding overdiagnosis persist, potentially leading to unnecessary patient stress and increased costs.
A groundbreaking study conducted by researchers at Harbin Medical University in China undertook a meticulous review of randomized controlled trials to assess the advantages and disadvantages of AI-based systems in adenoma detection, comparing them against conventional colonoscopy methods. This comprehensive meta-analysis aimed to deepen our understanding of AI-assisted detection of colorectal neoplasia. The findings were compelling, revealing that AI-enhanced colonoscopy methods significantly elevated the detection rates of colorectal neoplasia, concurrently reducing the rates of missed adenomas and polyps. Moreover, these AI-assisted studies reported substantial increases in both polyp and adenoma detection rates, including the average number of adenomas and polyps identified per colonoscopy procedure.
To elaborate, the miss rate for polyps using AI-based colonoscopy methods witnessed a remarkable reduction of 52.5%, coupled with a noteworthy 23.8% increase in the polyp detection rate compared to standard procedures. The number of polyps discovered per colonoscopy showed an uptick of 0.271 when employing AI-based methods. Similarly, the adenoma detection rate experienced a notable improvement of 24.2%, with a significant 50.5% decrease in the adenoma miss rate using AI methods. On average, there was an additional detection of 0.202 adenomas per colonoscopy through AI-enhanced detection techniques. However, it is essential to note the substantial heterogeneity observed in the outcomes related to polyp and adenoma detection across these studies.
In conclusion, the study's findings strongly suggest that AI-integrated colonoscopy holds immense promise in substantially improving adenoma and colorectal neoplasia detection rates. The minor enhancements in colonoscopy quality facilitated by AI could translate into significant benefits for large-scale colorectal cancer screening programs, ensuring both uniformity and elevated quality in colonoscopy procedures. While acknowledging these advancements, the research team underscores the imperative need for further long-term studies to validate the sustained effectiveness of AI-based colonoscopy methods in reducing the rates of morbidity and mortality associated with colorectal cancer. Stay informed about the evolving landscape of colorectal cancer screening, where AI in healthcare plays a pivotal role in enabling early diagnosis for improved patient outcomes.
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